From the USA: Bilateral Wilms Tumors That Grow During Chemo Mostly Stromal-Predominant

Bilateral Wilms tumors (BWTs) that increase in size during neoadjuvant chemotherapy, especially in younger patients, are most often stromal-predominant, according to a study published online March 27 in the Journal of the National Cancer Institute.

Colton Duncan, from the Dana-Farber Cancer Institute/Boston Children’s Hospital, and colleagues conducted a retrospective, single-institution study to examine whether initial chemotherapy response is associated with tumor histology among patients with BWT who underwent surgery from January 2000 to March 2022. A total of 68 patients were eligible for the study.

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