From the UK: Increased Morbidity Risks Seen for Male, Female p.C282Y Homozygotes
Male and female p.C282Y homozygotes, including those undiagnosed with hemochromatosis, have increased morbidity risks, according to a study published in the March issue of BMJ Open.
Mitchell R. Lucas, from the University of Exeter in the United Kingdom, and colleagues conducted a prospective cohort study in the U.K. Biobank (2006 to 2010) involving 451,270 participants who were genetically similar to the 1,000 Genomes European reference population. Incident clinical outcomes and mortality were compared for those with HFE p.C282Y/p.H63D mutations and those without variants.
Source: Advances and More licensed by HealthDay
