Directly from the UK: Inorganic Nitrate Treatment Cuts Rate of Contrast-Induced Nephropathy

For patients presenting with acute coronary syndromes (ACS) undergoing coronary angiography, inorganic nitrate treatment reduces the rate of contrast-induced nephropathy (CIN), according to a study published online March 21 in the European Heart Journal.

Daniel A. Jones, M.D., Ph.D., from the Queen Mary University of London, and colleagues conducted a double-blind, randomized trial to assess the efficacy of inorganic nitrate in CIN prevention in at-risk patients presenting with ACS. Patients were randomly assigned to receive once-daily potassium nitrate (12 mmol) or placebo (319 and 321, respectively) for five days.

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