Dazodalibep significantly improves disease activity and swollen and tender joint counts in patients with moderate-to-severe active rheumatoid arthritis (RA), according to new findings from the Phase 2 MIDORA clinical trial.
The drug, a non-antibody fusion protein that targets CD40L, also reduced biomarkers of T- and B-cell costimulatory blockage and inhibited germinal center formation activity and autoantibody production, in a population with RA.
Source: MDMag
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