USA: Risk for Autoimmune Inflammatory Rheumatic Disease Increased After SARS-CoV-2

Patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have an increased risk for incident autoimmune inflammatory rheumatic disease (AIRD) compared with matched patients with influenza infection or uninfected controls, according to a study published online March 5 in the Annals of Internal Medicine.

Min Seo Kim, M.D., from the Broad Institute of MIT and Harvard in Boston, and colleagues examined the effect of COVID-19 on the long-term risk for incident AIRD during various follow-up periods in a binational, longitudinal study. Data were included for 10,027,506 Korean and 12,218,680 Japanese patients aged 20 years or older, including those with COVID-19 matched to patients with influenza and uninfected controls. The primary outcome was AIRD onset one, six, and 12 months after infection or matched index date.

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