UK: Distinctive Gut Microbial Composition Seen for Progressors to Rheumatoid Arthritis
At-risk individuals who progress to rheumatoid arthritis (RA) have a distinctive gut microbial composition, according to a study published online Nov. 7 in the Annals of the Rheumatic Diseases.
Christopher M. Rooney, from the University of Leeds in the United Kingdom, and colleagues examined structural, functional, and temporal changes in the gut microbiome among individuals who did versus those who did not progress to RA. A total of 124 individuals at risk for RA, defined by the presence of anticyclic citrullinated protein (anti-CCP) antibodies and new musculoskeletal symptoms, were identified (30 progressed to RA); 19 underwent longitudinal sampling at five time points over 15 months (five progressed to RA).
Source: Advances and More licensed by HealthDay
