The Netherlands: Multitarget Fecal Immunochemical Test Increases Detection of Advanced Adenoma

The multitarget fecal immunochemical test (mtFIT), which measures hemoglobin, calprotectin, and serpin family F member 2, yields higher detection of advanced adenoma than FIT, according to a study published online Feb. 9 in The Lancet Oncology.

Pieter H. A. Wisse, M.D., from the Netherlands Cancer Institute in Amsterdam, and colleagues examined the clinical utility of mtFIT versus FIT in a setting of population-based colorectal cancer screening among individuals aged 55 to 75 years who were eligible for the Dutch national FIT-based colorectal cancer screening program. Positive FIT or mtFIT resulted in a colonoscopy referral.

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