Reporting from the USA: Mesenchymal Stem Cell-Neural Progenitors Beneficial for MS

Select patients with progressive multiple sclerosis (MS) may benefit from mesenchymal stem cell-neural progenitors (MSC-NPs), according to a study published online May 23 in Stem Cell Research & Therapy.

Violaine K. Harris, Ph.D., from the Tisch Multiple Sclerosis Research Center of New York in New York City, and colleagues conducted a randomized, double-blind trial with a compassionate crossover design at a single site. Participants were stratified according to the baseline Expanded Disability Status Scale (EDSS, 3.0 to 6.5) and disease subtype (secondary or primary progressive MS) and were randomly allocated to treatment (six intrathecal [IT] injections of autologous MSC-NPs) or placebo (saline) every two months (27 in each group).

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