Reporting from Italy: Amino Acids Reduced Acute Kidney Injury After Cardiac Surgery

Among adult patients undergoing cardiac surgery, infusion of amino acids reduces the occurrence of acute kidney injury (AKI), according to a study published online June 12 in the New England Journal of Medicine to coincide with the annual Critical Care Reviews Meeting, held from June 12 to 14 in Belfast, Northern Ireland.

Giovanni Landoni, M.D., from the IRCCS San Raffaele Scientific Institute in Milan, and colleagues examined the efficacy of amino acids in reducing the occurrence of AKI after cardiac surgery. The analysis included 3,511 adult patients who were scheduled to undergo cardiac surgery with cardiopulmonary bypass who were randomly assigned to receive an intravenous infusion of either a balanced mixture of amino acids (2 g per kilogram of ideal body weight per day) or placebo (Ringer’s solution) for up to three days.

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