Lupus is caused by a specific defect in the immune system that can be reversed, potentially curing the autoimmune disorder, a new study claims.
The disease appears to be caused by malfunctions in an immune system pathway that regulates cells’ response to environmental pollutants, bacteria and toxins.
Insufficient activation of this pathway, controlled by the aryl hydrocarbon receptor (AHR), results in an overproduction of immune cells that attack the body itself rather than foreign invaders, researchers said.
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