From the USA: Reduced Levels of CSF β-Amyloid Seen in Veterans With Blast-Related mTBI

Middle-aged veterans with blast-related mild traumatic brain injury (mTBI) have reduced levels of cerebrospinal fluid (CSF) β-amyloid (Aβ), according to a study published online March 13 in Neurology.

Ge Li, M.D., Ph.D., from the Veterans Affairs Northwest Mental Illness Research, Education, and Clinical Center in Seattle, and colleagues conducted a cross-sectional study of veterans with blast-related mTBI and non-mTBI veterans and civilians to examine early changes using CSF biomarkers. Participants underwent standardized clinical and neuropsychological assessments and lumbar puncture for CSF collection. The sample included 51 participants with mTBI and 85 non-mTBI participants.

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