Neoadjuvant chemotherapy (NAC) with lymphadenectomy for locally advanced penile squamous cell carcinoma (PSCC) is well tolerated and improves outcomes, according to a study published online Feb. 16 in the Journal of the National Cancer Institute.
Kyle M. Rose, M.D., from the Ochsner Medical Center in New Orleans, and colleagues investigated the efficacy and safety of NAC for locally advanced PSCC. The analysis included 209 patients (7 percent with stage II disease, 48 percent with stage III, and 45 percent with stage IV).
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