From the UK: Selenium Not Linked to Recurrence of Non-Muscle-Invasive Bladder Cancer

For patients with non-muscle-invasive bladder cancer (NMIBC), selenium supplementation does not reduce the risk for recurrence, while vitamin E is associated with an increased risk for recurrence, according to a study published online Oct. 17 in JAMA Network Open.

Richard T. Bryan, Ph.D., from the University of Birmingham in the United Kingdom, and colleagues conducted a multicenter study involving patients with newly diagnosed NMIBC recruited from 10 secondary or tertiary care hospitals. Two hundred seventy patients were randomly assigned to selenium plus placebo, vitamin E plus placebo, selenium plus vitamin E, and placebo plus placebo in a double-blind manner (65, 71, 69, and 65 patients, respectively).

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