From France: EEG Most Beneficial Tool for Managing CAR T-Cell-Related Neurotoxicity

For patients with immune effector cell-associated neurotoxicity syndrome (ICANS) due to chimeric antigen receptor (CAR) T-cell therapy, electroencephalogram (EEG) has the greatest therapeutic impact, according to a study published online March 19 in Blood Advances.

Mattéo Mauget, M.D., from the University Hospital of Rennes in France, and colleagues describe the role of magnetic resonance imaging (MRI), lumbar puncture (LP), and EEG in the management of ICANS in a cohort of real-life patients treated with CAR T-cell therapy. A total of 190 consecutive patients were treated with CAR T-cell therapy between August 2018 and January 2023.

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