From Canada: Simple Hysterectomy Not Inferior for Pelvic Recurrence in Cervical Cancer

For patients with low-risk cervical cancer, simple hysterectomy is not inferior to radical hysterectomy with respect to incidence of pelvic recurrence at three years, according to a study published in the Feb. 29 issue of the New England Journal of Medicine.

Marie Plante, M.D., from Centre Hospitalier Universitaire de Québec in Canada, and colleagues conducted a multicenter noninferiority trial comparing radical hysterectomy to simple hysterectomy including lymph-node assessment in patients with low-risk cervical cancer (350 patients in each group). The prespecified noninferiority margin was 4 percentage points for the between-group difference in pelvic recurrence at three years.

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