From Australia: Risk for Alzheimer Dementia Lower With Treated Versus Untreated HTN

Individuals with treated hypertension have a reduced risk for Alzheimer dementia (AD) compared with those with untreated hypertension, according to research published online Aug. 14 in Neurology.

Matthew J. Lennon, M.D., from the University of New South Wales in Sydney, and colleagues examined whether previous hypertension or antihypertensive use modifies AD or non-AD (all-cause dementia) risk in late life in an individual participant data meta-analysis that included community-based longitudinal studies of aging. The risks for developing AD and non-AD were examined as the main outcomes, while the main exposures were hypertension history/antihypertensive use and baseline systolic and diastolic blood pressure (BP). The analysis included 31,250 participants (mean baseline age, 72 years) from 14 nations.

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