Directly from the USA: Antihypertensive Combos Recommended for BTKi-Linked Hypertension

Specific combinations of antihypertensives are recommended for patients with Bruton’s tyrosine kinase inhibitor (BTKi)-associated hypertension (HTN), according to a study published online Feb. 5 in Blood Advances.

Laura Samples, M.D., from the Fred Hutchinson Cancer Center in Seattle, and colleagues examined the optimal treatment of BTKi-associated HTN in a study involving randomly selected patients with lymphoid malignancies on a BTKi and antihypertensive drugs with at least three months of follow-up data. Participants were classified as those diagnosed with HTN prior to BTKi initiation (prior HTN; 118 patients) and those diagnosed after BTKi initiation (de novo HTN; 78 patients).

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