Directly from Japan: Gastroesophageal Reflux Disease Increases Risk for Atrial Fibrillation

Gastroesophageal reflux disease (GERD) is associated with an increased incidence of atrial fibrillation, according to a study published online June 2 in Frontiers in Cardiovascular Medicine.

Lei Wang and Yi Wei Lu, from the Aerospace Center Hospital in Beijing, and colleagues assessed GERD’s role as a potential contributing factor in atrial fibrillation using a two-sample Mendelian randomization technique. The examination of the association of genetic variants with GERD used data from a genome-wide association study (GWAS) of 602,604 people, while data on the association between genetic variations and atrial fibrillation was obtained from a second GWAS involving 1.03 million participants.

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