China: ChemoRT Then Immunochemotherapy Then Surgery Promising in Unresectable Esophageal Cancer
For patients with unresectable locally advanced esophageal squamous cell carcinoma (ESCC), chemoradiotherapy (CRT) followed by immunochemotherapy (iCT) and then surgery is promising, according to a study published online Nov. 15 in Clinical Cancer Research.
Xin Wang, from the Chinese Academy of Medical Sciences and Peking Union Medical College in Beijing, and colleagues examined the safety and efficacy of CRT followed by iCT and surgery for unresectable locally advanced ESCC. Patients received radiotherapy and nab-paclitaxel plus cisplatin for five weeks, followed by tislelizumab plus chemotherapy (nab-paclitaxel and cisplatin) for two 21-day cycles. Patients who converted to resectable then underwent surgery. One-year progression-free survival (PFS) was the primary end point.
Source: Advances and More licensed by HealthDay
